Recrudescence of Focal Stroke Symptoms during Pain Management with Hydromorphone
نویسندگان
چکیده
منابع مشابه
Recrudescence of Focal Stroke Symptoms during Pain Management with Hydromorphone
Patients who have recovered from a prior stroke may experience a reemergence of their original stroke syndrome secondary to metabolic derangements, sedation, infection, and/or fatigue. Critically, the molecular/cellular mechanisms mediating symptom recurrence after exposure to analgesic agents remain unknown. Accordingly, herein, we report a unique case of a patient with hydromorphone-induced r...
متن کاملClinical application of extended-release hydromorphone for pain management
Hydromorphone is a semi-synthetic μ-agonist commercially available in oral, rectal and injectable formulations for the control of acute and chronic pain [1]. Hydromorphone is typically used for moderate-to-severe pain, and is an effective alternative to morphine [1]. Like other μ-agonists in the opioid family there is no ceiling effect for hydromorphone, and cross-tolerance with other opioids i...
متن کاملHydromorphone in elderly patients with polypathia and with severe pain
S u m m a r y There continue to exist serious deficiencies in the analgesic therapy of elderly patients and patients with polypathia and severe pain. Orally administered controlled-release hydromorphone (see Note 1) appears to be particularly suitable for this patient group due to its pharmacological and metabolic benefits. The aim of the present prospective, multicentre study was to analyse th...
متن کاملPain management in chronic kidney disease: the pharmacokinetics and pharmacodynamics of hydromorphone and hydromorphone-3-glucuronide in hemodialysis patients.
OBJECTIVE To describe the pharmacokinetics of hydromorphone (HM) and its primary metabolite hydromorphone-3-glucuronide (H3G) both on and off dialysis in relation to the pharmacodynamic measurements of pain. DESIGN Prospective, open-label, observational study. SETTING Canadian, university-based renal program. PARTICIPANTS Twelve anuric hemodialysis patients with chronic pain, established ...
متن کاملManagement of shoulder pain in patients with stroke.
Shoulder pain affects from 16% to 72% of patients after a cerebrovascular accident. Hemiplegic shoulder pain causes considerable distress and reduced activity and can markedly hinder rehabilitation. The aetiology of hemiplegic shoulder pain is probably multifactorial. The ideal management of hemiplegic stroke pain is prevention. For prophylaxis to be effective, it must begin immediately after t...
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ژورنال
عنوان ژورنال: Frontiers in Neurology
سال: 2016
ISSN: 1664-2295
DOI: 10.3389/fneur.2016.00050